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Fresh Raw Semen vs Frozen (cryopreserved) Semen

Submitted by: trent on May 2, 2009 - (Last updated: Dec 24, 2011)

 

Source Non-Frozen Frozen Quotes

Lesbian Parents and Insurance for Fertility Treatments - Rainbow Babies

"20 to 30 percent" "8 and 15 percent"

"The success rate for conceiving with frozen sperm hovers between 8 and 15 percent, compared with a 20 to 30 percent chance of conceiving during intercourse"
 
Fresh vs. frozen sperm - Choice Moms
 		     "Fresh sperm is more effective for achieving pregnancy than sperm that has been frozen and thawed," she says. "Many women don't realize that the quantity of semen they are receiving from a bank is only 0.5cc, while the normal volume of a man's ejaculate is 3-5cc. And fresh sperm that is inseminated vaginally lives for up to 72 hours, or three days. When sperm is frozen for quarantine, or purchased from a sperm bank, the lifespan of the sperm is reduced to about 24 hours when inseminated vaginally. With intrauterine insemination, excellent timing is imperative, as sperm only live for 6-8 hours once they are placed directly into the uterus."

Click below for a slide show from a Stanford University doctor titled "Acheiving Pregnancy Using Fresh Versus Cryopreserved Semen for Donor Insemination".  The slide show can also be seen on the FDA website:
http://www.fda.gov/ohrms/dockets/ac/01/briefing/3817b2_12_lamb_files/frame.htm

Summary of presentation:

  • There would be 0.1 (zero point one) women per year infected with HIV if all 80,000 inseminations in 2001 used fresh sperm (slide 20)
     
  • Live births would increase by about 25% (slide 20)
     

Other notes:

  • "The risk of using fresh semen in donor insemination is quite small, in the range of risks we accept on a daily basis." 

  • "The reward, a better chance of having a family, is substantial."

  • People born from fresh semen are known to live longer than people born from frozen semen by about one year (slide 21)

  • "Informed patients may reasonably accept this risk to obtain this reward, if given the opportunity."
      

Source: "Acheiving Pregnancy Using Fresh Versus Cryopreserved Semen for Donor Insemination" Blood Products Advisory Committee, 12/14/01" Food and Drug Administration

Powerpoint Source:  http://www.fda.gov/ohrms/dockets/AC/01/briefing/3817b2_12_lamb.ppt


 

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